The HDL-Atherosclerosis Treatment Study (HATS), a three-year randomized controlled trial in 160 patients with documented CHD and low HDL concentrations, found that a combination of simvastatin and nicotinic acid (2-3 g/day) increased HDL concentrations, inhibited the progression of coronary artery stenosis (narrowing), and decreased the frequency of cardiovascular events, including myocardial infarction and stroke, compared to placebo (88)
The small S
Multidisciplinary care involving physicians, dietitians, diabetes educators, and mental health professionals optimizes outcomes and addresses the complex pathophysiology of metabolic disease
Patients who see the best results treat it as a non-negotiable part of their daily evening routine
R., Revnic, F., Paltineanu, B
Oct 2002;56(8):365-79